"loathèd med'cine"IronyAct 3,Scene 2Line 265An explanation of the irony in the phrase “loathèd med’cine” in Act 3, Scene 2 of myShakespeare’s A Midsummer Night’s Dream. Lysander Out, loathèd med’cine. O hated potion, hence. It's ironic that Lysander is comparing Hermia to a harmful drug when it’s the love juice from Robin he's suffering from.